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Effectiveness of oral pressure therapy in obstructive sleep apnea: a systematic analysis

Conclusions Although there was a significant reduction in AHI with OPT, the baseline AHI was not suppressed in majority of patients to the extent to call these patients as optimally treated. Successful treatment with OPT did not correlate with severity of OSA; however, patients with retro-palatal collapse responded better to treatment. Further research is needed to identify OSA patients who would benefit with this treatment modality. (Source: Sleep and Breathing)

State-of-the-Art Imaging of the Lung for Connective Tissue Disease (CTD)

Abstract Involvement of the respiratory system is common in connective tissue diseases (CTDs), and the resultant lung injury can affect every part of the lung: the pleura, alveoli, interstitium, vasculature, lymphatic tissue, and large and/or small airways. Most of the parenchymal manifestations of CTD are similar to those found in interstitial lung diseases (ILDs), especially idiopathic interstitial pneumonias, and can be classified using the same system. Although there is some overlap, each CTD is associated with a characteristic pattern of pulmonary involvement. For this reason, thin-section CT as well as pulmonary function tests and serum markers are utilized for diagnosis, disease severity assessment, and therapeutic efficacy evaluation of ILD associated with CTD. In additio...

Your NEJM Group Today: Pneumonia & Respiratory Failure, How to Improve the Flu Vaccine, South Dakota EM Opportunity (FREE)

By the Editors NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today:NEJM Clinical Practice Center: Case Record …

Noninvasive ventilation during exercise training beneficial in patients with COPD

(American College of Chest Physicians) Researchers from Turkey's Ege University Department of Biostatistics evaluated the effects of noninvasive ventilation and supplemental oxygen during exercise training and found it to have multiple physiologic benefits in patients with severe COPD. Results showed that supplemental oxygen during exercise helped to reduce hyperinflation and improve respiratory muscle function and exercise capacity. (Source: EurekAlert! - Medicine and Health)

Blood or sputum eosinophils to guide asthma therapy?

Publication date: Available online 19 October 2015 Source:The Lancet Respiratory Medicine Author(s): Manali Mukherjee, Parameswaran Nair (Source: The Lancet Respiratory Medicine)

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