Login to your account

Username *
Password *
Remember Me

Blog With Right Sidebar

    Vous êtes ici :  
  1. Accueil
  2. Blog With Right Sidebar

Outpatient management of pulmonary embolism

This multi-national, randomised trial compared outpatient versus inpatient care in patients with acute pulmonary embolism with a low risk of death (severity index category of I or II). Both groups were treated with enoxaparin (≥5 days) and oral anticoagulation (≥90 days). One of the 171 outpatients and none of the 168 inpatients had recurrence of venous thromboembolism within 90 days, meeting the non-inferiority criteria (<4% between group difference).

With respect to secondary outcomes, two outpatients and no inpatients had major bleeding (intramuscular haematomas) within 14 days. There was one death in each group, neither related to the trial. There was no statistically significant difference in use of medical resources between groups. However, the outpatient...

Screening for lung cancer: we still need to know more

The holy grail for a screening test is that it discovers more cancers in the screened arm than in the control; that those cancers are of an earlier stage and there is, as a consequence, a stage shift towards lower stage cancers compared with the control group; that the test is acceptable to, basically, healthy individuals with low risks of serious side effects resulting from tests following a positive screen; and that the cost of a life saved, or a quality-adjusted life-year (QALY) is acceptable to the economy of the day.

Published in Thorax there is an end-of-screening report on a Danish CT-based study. They entered 4104 men and women, (of which 45% were women, unusually high) aged between 50 and 70 years, a 20 pack-year smoking history; lung function was recorded but was not used a...

Novel strategies for the management of right ventricular failure with pulmonary hypertension

The authors report a case where four novel strategies were successfully used in the management of advanced right ventricular failure with severe pulmonary hypertension and complex adult congenital heart disease. These included combination and optimisation of three advanced therapies for pulmonary hypertension, therapeutic abdominal paracentesis, correction of underlying metabolic/endocrine disturbance and a new inotropic agent.

CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT

CT screening for lung cancer brings forward early disease, and at this point no stage shift or reduction in mortality was observed. More lung cancers were diagnosed in the screening group, indicating some degree of overdiagnosis and need for longer follow-up.

Compliance with home non‐invasive ventilation

Home non‐invasive ventilation (NIV) is being increasingly employed to treat chronic hypercapnic respiratory failure (CHcRF). However, there is little data on compliance with home NIV. Sixty‐five patients, aged 72.6 ± 9.4 years, who were using home NIV were administered a questionnaire on symptomatology and adverse effects associated with home NIV. Mean daily use of home NIV was 7.3 ± 2.9 h/day and the median percentage of days on which home NIV was used for ≥4 h/day was 96.7%.© 2012 The Authors. Respirology © 2012 Asian Pacific Society of Respirology

Search

Search