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[Editorial] MERS-CoV: address the knowledge gaps to move forward

The first and second cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the USA were reported by the Indiana State Department of Health and the Florida Department of Health on May 1 and May 11, respectively, to the Centers for Disease Control and Prevention. These two cases, like all previous cases reported worldwide, have a Middle Eastern connection. (Source: LANCET)

UN agriculture agency urges more research into role of animals in spreading MERS virus

Health experts and veterinarians called for stepped-up monitoring, investigations and immediate reporting of cases of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) during a meeting convened by the Food and Agricultural Organization (FAO) in Oman. (Source: UN News Centre - Health, Poverty, Food Security)

Nontuberculous Mycobacteria in Respiratory Infections: Advances in Diagnosis and Identification

An urgent question that needs to be addressed rapidly by the mycobacteriology laboratory is whether Mycobacterium tuberculosis complex or NTM is involved. NAA assays are excellent tools for the purpose, and can be used directly on the clinical specimens of patients suspected of having mycobacterial disease, allowing same-day reporting of results. The CDC recommends using both liquid and solid media for growth detection of mycobacteria to decrease the time to detection and to increase the yield of growth detection. DNA sequencing of variable genomic regions offers a rapid, accurate, and relatively inexpensive method for the identification of mycobacteria. (Source: Clinics in Laboratory Medicine)

Rapid Diagnosis of Influenza: State of the Art

Much effort has been expended developing testing modalities for influenza viruses that are capable of providing rapid results to clinicians. Antigen-detection techniques, historically the only methods able to deliver results quickly, are still widely used despite concerns about sensitivity. Recently, nucleic acid amplification tests (NAATs), which can achieve rapid turnaround times and high sensitivity, have become available. In addition, NAATs can detect other respiratory pathogens. Although there are many theoretical advantages to rapid influenza testing, the clinical impact of testing in various patient populations must be considered against the cost and the analytical performance of the tests. (Source: Clinics in Laboratory Medicine)

Changes in Gene Expression From Patients With Asthma, RhinitisChanges in Gene Expression From Patients With Asthma, Rhinitis

Discover more about how dsRNA changes transcriptional profiles of primary nasal and bronchial epithelial cells - from patients with allergic rhinitis. Respiratory Research (Source: Medscape Today Headlines)

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