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Point/Counterpoint: Should asymptomatic OSA be treated in patients with significant cardiovascular disease?

POINT: Should Asymptomatic OSA Be Treated in Patients With Significant Cardiovascular Disease? Yes – CHEST COUNTERPOINT: Should Asymptomatic OSA Be Treated in Patients With Significant Cardiovascular Disease? No – CHEST  

The post Point/Counterpoint: Should asymptomatic OSA be treated in patients with significant cardiovascular disease? appeared first on Links Medicus.

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study.

Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study (the ECHO-COVID study) – Intensive Care Medicine   Commentary on Twitter Echocardiography in #COVID19 #ICU pts, ECHO-COVID study ♥︎ systolic dysfunction in ⅓: 23% LV (similar to septic cardiomyopathy), 22.5% RV (due to P overload)♥︎ ACP in 17% (due to hypercapnia, […]

The post Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study. appeared first on Links Medicus.

RCT: Segmentectomy resulted in better outcomes than lobectomy in small-sized peripheral non-small-cell lung cancer.

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)  

The post RCT: Segmentectomy resulted in better outcomes than lobectomy in small-sized peripheral non-small-cell lung cancer. appeared first on Links Medicus.

One-year follow-up of a RCT: In ICU patients with severe hypoxemia, there was no difference in long-term mortality and health-related quality of life with lower vs. higher oxygenation targets.

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine Original Study: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine   Commentary on Twitter Lower (8 kPa) vs higher oxygenation (12 kPa) targets: no […]

The post One-year follow-up of a RCT: In ICU patients with severe hypoxemia, there was no difference in long-term mortality and health-related quality of life with lower vs. higher oxygenation targets. appeared first on Links Medicus.

WHO recommends highly successful COVID-19 therapy (nirmatrelvir-ritonavir) and calls for wide geographical distribution and transparency from originator.

WHO recommends highly successful COVID-19 therapy and calls for wide geographical distribution and transparency from originator – World Health Organization See also: A living WHO guideline on drugs for covid-19 – The BMJ Therapeutics and COVID-19: living guideline – World Health Organization Related: Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal […]

The post WHO recommends highly successful COVID-19 therapy (nirmatrelvir-ritonavir) and calls for wide geographical distribution and transparency from originator. appeared first on Links Medicus.

Cohort study: COVID-19 infection granted patients strong and long-lasting protection from reinfection.

News Release: COVID-19 infection granted patients strong and long-lasting protection from reinfection – Providence Health & Services Original Study: Rates of COVID-19 Among Unvaccinated Adults With Prior COVID-19 – JAMA Network Open Commentary: COVID-19 infection may offer similar immunity as vaccination – CIDRAP   Commentary on Twitter This US cohort study found that unvaccinated individuals […]

The post Cohort study: COVID-19 infection granted patients strong and long-lasting protection from reinfection. appeared first on Links Medicus.

RCT: Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for prevention of Covid-19.

Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 – New England Journal of Medicine   Commentary on Twitter AZD7442 (tixagevimab/cilgavimab) found to have about 76% efficacy in preventing symptomatic Covid-19 infection. https://t.co/8tmvz3xI4I pic.twitter.com/fOegZjBRA6 — NEJM (@NEJM) April 20, 2022  

The post RCT: Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for prevention of Covid-19. appeared first on Links Medicus.

A nonrandomized controlled study found awake prone position (median of 4.2 hours per day) may not benefit hospitalized adults with Covid-19.

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine Commentaries: Prone Positioning for Nonintubated Patients With COVID-19—Potential Dangers of Extrapolation and Intermediate Outcome Variables – JAMA Internal Medicine Study suggests worse outcomes for awake COVID patients in prone position – CIDRAP Putting Hospitalized COVID Patients on […]

The post A nonrandomized controlled study found awake prone position (median of 4.2 hours per day) may not benefit hospitalized adults with Covid-19. appeared first on Links Medicus.

Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel.

Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel – STAT  

The post Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel. appeared first on Links Medicus.

M-A: Global prevalence of post COVID-19 condition or long COVID.

Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review – The Journal of Infectious Diseases Commentary: Global data reveal half may have long COVID 4 months on – CIDRAP   Commentary on Twitter (thread – click for more) ?The so far largest meta-analysis of more than 1.5 million infected individuals […]

The post M-A: Global prevalence of post COVID-19 condition or long COVID. appeared first on Links Medicus.

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