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Chinese COVID-19 vaccine maintains protection in variant-plagued Brazil

Chinese COVID-19 vaccine maintains protection in variant-plagued Brazil – Science Original study: [Preprint] CoronaVac is 50% effective for reducing symptomatic SARS-CoV-2 infection after the first dose in the setting of high P.1 variant transmission in Brazil (study and commentary on Twitter)  

The post Chinese COVID-19 vaccine maintains protection in variant-plagued Brazil appeared first on Links Medicus.

[Preprint] Efficacy and safety of CoronaVac in healthcare professionals in Brazil

Efficacy and Safety of a COVID-19 Inactivated Vaccine in Healthcare Professionals in Brazil: The PROFISCOV Study – SSRN   Commentary on Twitter (thread – click for more) Preprint on Brazilian trial by @butantanoficial of Sinovac's CoronaVac, 2 weeks apart. Data for 9,823 people who had 2 doses, 12,396 after 1 dose.The P1 ("Brazilian") variant of […]

The post [Preprint] Efficacy and safety of CoronaVac in healthcare professionals in Brazil appeared first on Links Medicus.

EMA Reviews Link Between Blood Clots and Johnson & Johnson Vaccine

EMA Reviews Link Between Blood Clots and Johnson & Johnson Vaccine – Health Policy Watch See also: Johnson & Johnson’s COVID-19 vaccine under scrutiny at EMA after 4 ‘serious cases’ of unusual blood clots – Fierce Pharma AND J&J COVID-19 vaccine under EU review over blood clots, AstraZeneca probe grows – Reuters  

The post EMA Reviews Link Between Blood Clots and Johnson & Johnson Vaccine appeared first on Links Medicus.

Papers Confirm Rare Thrombocytopenia Link to AstraZeneca Vaccine

Papers Confirm Rare Thrombocytopenia Link to AstraZeneca Vaccine – TCTMD Study 1: Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination – New England Journal of Medicine Study 2: Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination – New England Journal of Medicine  

The post Papers Confirm Rare Thrombocytopenia Link to AstraZeneca Vaccine appeared first on Links Medicus.

Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients

Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients – Critical Care   Commentary on Twitter Prone position in #COVID19, use & effect:➡️PP widely adopted, the more severe the respiratory failure, the more frequent the use➡️PP improved oxygenation in most (better V/Q matching?)➡️mortality of O2-Non-Responders significantly higher@Crit_Care […]

The post Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients appeared first on Links Medicus.

Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial – The Lancet Respiratory Medicine Commentary: Early treatment with inhaled budesonide to prevent clinical deterioration in patients with COVID-19 – The Lancet Respiratory Medicine   Commentary on Twitter NEW Research— Early administration of inhaled budesonide reduced the likelihood of […]

The post Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19 appeared first on Links Medicus.

[Preprint] Pfizer vaccine less effective for SARS-CoV-2 variant B.1.351

Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals – medRxiv Commentaries: South African variant may evade protection from Pfizer vaccine, Israeli study says – Reuters AND Israeli data shows South African variant able to ‘break through’ Pfizer vaccine – The Times of Israel Related: Another study indicates SARS-CoV-2 […]

The post [Preprint] Pfizer vaccine less effective for SARS-CoV-2 variant B.1.351 appeared first on Links Medicus.

Comprehensive Review | Pneumonia

Pneumonia – Nature Reviews Disease Primers (free for a limited period) Try this link if the above is paywalled.  

The post Comprehensive Review | Pneumonia appeared first on Links Medicus.

Commentary | Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes?

Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology  

The post Commentary | Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes? appeared first on Links Medicus.

The NIH COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19

The COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19 – NIH COVID-19 Treatment Guidelines  

The post The NIH COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19 appeared first on Links Medicus.