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Population-based trends in use of surgery for non-small cell lung cancer in a UK region, 1995-2006

Objective

To assess time trends in use of surgery in patients with non-small cell lung cancer (NSCLC) in a UK region.

 Methods

Cancer registration data for patients diagnosed with NSCLC between 1995 and 2006 in the East of England were analysed. Rates of surgery use for different age, gender, diagnosis period, tumour subtype and deprivation quintile groups were examined.

 Results

The analysis included 18 767 patients with NSCLC. During the study period, 13% of patients were treated by surgery. Use of surgery decreased over time from 15% in 1995–1997 to 11% in 2004–2006 (p=0.022). Initial socioeconomic differences in surgery use narrowed significantly over time (p=0.028) and became non-apparent at the end of the study period.

 Conclusions

Use of surgery in patients with NSCLC decreased during the study period, possibly reflecting increasing quality of preoperative staging processes. Initial socioeconomic inequalities in surgery use became undetectable at the end of the study period. The findings provide baseline information to support comparisons with patterns of clinical management in more recent years.

[The role of non-invasive ventilation in the treatment of chronic obstructive pulmonary disease.]

Authors: Nasiłowski J Non-invasive ventilation (NIV) is one of the most important developments in pulmonology over the past 15 years. Physiologic effect of NIV is the same as that of invasive ventilation and consists of unloading respiratory muscles and improving oxygenation. Nevertheless avoidance of ominous complications of intubation gives important advantages of NIV over invasive ventilation. The principal indication for NIV is severe exacerbation of COPD, with uncompensated respiratory acidosis. The efficacy of NIV in such population was proved, in controlled trials, to reduce: in-hospital mortality, the need for intubation, the rate of complications and the length of stay in ICU and hospital. The role of NIV in the treatment of COPD patients in stable state is less evident. Howe...

Short antibiotic courses safer for breathing-tube infections in children

Short courses of antibiotics appear just as effective as longer ones -- and a great deal safer -- in treating respiratory infections that might cause pneumonia in children on temporary breathing devices, according to a Johns Hopkins Children's Center study published online May 3 in Clinical Infectious Diseases. (Source: ScienceDaily Headlines)

Sleep magnetic resonance imaging: Dynamic characteristics of the airway during sleep in obstructive sleep apnea syndrome

Conclusions:Sleep MRI is a novel and reliable approach to simultaneously evaluate airway obstructions and respiratory events in real time during natural sleep. Sleep MRI can define the dynamic characteristics of airway obstruction in both surgically naive and postsurgical OSA patients. (Source: The Laryngoscope)

Five Things You Don't Know About Springtime Asthma

With spring comes birds, bees and for some, a wheeze. More than 24 million Americans have been diagnosed with asthma, but millions more may be at risk for the condition and not know it. Allergists who are members of the American College of Allergy, Asthma and Immunology (ACAAI) want people to be aware of these five little-known facts about asthma:

1. Sometimes the signs are subtle: Do you cough at night? Get winded while walking up stairs? These can be symptoms of asthma. "The lungs of a person who has asthma are inflamed all the time," said allergist Dr...

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