Login to your account

Username *
Password *
Remember Me

Blog With Right Sidebar

    Vous êtes ici :  
  1. Accueil
  2. Blog With Right Sidebar

The science behind the 7th edition Tumour, Node, Metastasis staging system for lung cancer

The Tumour, Node, Metastasis (TNM) system for classifying lung cancer is the cornerstone of modern lung cancer treatment and underpins comparative research; yet is continuously evolving through updated revisions.

The recently published Union for International Cancer Control 7th Edition TNM Classification for lung cancer addresses many of its predecessor's shortcomings and has been subject to rigorous evidence‐based methodology. It is based on a retrospective analysis of over 80000 lung cancer patients treated between 1990 and 2000 carried out by the International Association for the Study of Lung Cancer.

The dataset was truly international and included patients treated by all modalities. Extensive internal and external validation of the findings has ensured that the recommenda...

Evaluation of the asthma control test: A reliable determinant of disease stability and a predictor of future exacerbations

Conclusions : Single measurement of ACT is useful for assessing asthma control, prediction of exacerbation and changes in treatment decisions.

Efficacy and safety of indacaterol 150 and 300 µg in chronic obstructive pulmonary disease patients from six Asian areas including Japan: A 12‐week, placebo‐controlled study

Conclusions : Indacaterol provided clinically significant bronchodilation and improvements in dyspnoea and health status in Asian COPD patients.

Low‐dose Azithromycin improves phagocytosis of bacteria by both alveolar and monocyte‐derived macrophagesin COPD subjects

Conclusions :  The data provide further support for the long term use of low dose azithromycin as an attractive adjunct treatment option for COPD. Improved clearance of both apoptotic cells and bacteria in the airway may have a dual effect; reducing the risk of secondary necrosis and release of toxic cell contents that perpetuate inflammation as well as contributing to a reduction in the rate of exacerbations in COPD.© 2012

Tissue engineering for pulmonary diseases – insights from the laboratory

Advances in stem cell research and tissue engineering have opened new paradigms for future therapies toward many intractable diseases. Many tissue engineering approaches are also applied in the pulmonary research field.

Several materials have been utilized as scaffolds to support lung tissue engineering to recapitulate the three‐dimensional (3D) structure of the lung. Natural products and synthetic polymers are the two major components of the scaffold materials. Decellularization of allogeneic or xenogenic donor lungs is also utilized to obtain biological 3D matrix scaffolds. Decellularized lungs are recellularized with stem or progenitor cells. Cell sources are the key components for tissue engineering.

The best cell source for tissue engineering is autologous cells obtained fro...

 

Search

Search