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Applying biomarkers to clinical practice: a guide for utilizing procalcitonin assays

Prudent use of antimicrobial therapies is an important component in decreasing bacterial resistance. Procalcitonin (PCT) is a novel biomarker proposed as both a diagnostic and prognostic agent for use in various severe infections. Elevated PCT levels have a high sensitivity and specificity for diagnosing infections. This biomarker has been studied as an aid to identify patients requiring antimicrobial initiation, stratify infections according to severity and guide therapy durations. Two commercially available tests are approved for use in the USA. Other biomarkers have been studied for similar indications, but are subject to elevation from chronic inflammatory conditions and medications. The advantage of PCT over other biomarkers is due to the limited disease states and drug therapies that...

The prevalence of undiagnosed and undertreated Chronic Obstructive Pulmonary Disease in lung cancer population

Conclusions:  COPD is substantially underdiagnosed and undertreated in a hospitalized lung cancer population. History of smoking, respiratory diseases and symptoms promotes disease diagnosis. Education of COPD knowledge among patients and doctors are urgently required in this special population.© 2012 The Authors. Respirology © 2012 Asian Pacific Society of Respirology (Source: Respirology)

HPA: Update on new coronavirus

Source: Health Protection Agency (HPA) Area: News The Health Protection Agency (HPA) has published an update of the first case of severe respiratory illness associated with a new type of coronavirus, reported on 22 September 2012.

The agency notes that there have been no new cases reported in the UK and that to their knowledge there are only two cases worldwide.

No evidence of human-to-human transfer of new virus, says UN health agency

The United Nations World Health Organization (WHO) said today there was "no evidence" of human-to-human transmission of a new virus that can cause acute respiratory infection and renal failure, and whose discovery in a second patient last month spurred the agency to issue a global alert. (Source: UN News Centre - Health, Poverty, Food Security)

CT technique could improve COPD classification

The parametric response map technique can be used in chronic obstructive pulmonary disease to distinguish between disease subtypes, say US researchers. (Source: MedWire News - Respiratory)

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