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Cochrane: more evidence needed for NIPPV in stable COPD

The authors of a Cochrane systematic review say that they have failed to find evidence of a consistent beneficial effect of non-invasive positive pressure ventilation in hypercapnic patients with chronic obstructive pulmonary disease. (Source: MedWire News - Respiratory)

Cough in chronic obstructive pulmonary disease: is it important and what are the effects of treatment?

Professor Peter Calverley challenges some common preconceptions about cough in COPD and reasons that assessment and treatment of cough should have a more prominent place in the clinical management of the condition. (Source: Cough)

Mediated Fluticasone Uptake Across Calu‐3 Cells by Salmeterol as Combination Powder Inhaler

ConclusionsOur data demonstrates that salmeterol may decrease the permeability of epithelial cells, resulting in slower fluticasone transport across Calu‐3 epithelial monolayers. The subsequent increased residence time of fluticasone in the airways could prolong its anti‐inflammatory effects. (Source: Respirology)

MERS-CoV Claims Another Life In Saudi Arabia

Saudi health authorities confirmed that an 81-year-old male has died from MERS-CoV (Middle East Respiratory Syndrome Coronavirus) infection, bringing the death toll in the kingdom to 33. The Saudi Ministry of Health also confirmed that six new MERS-CoV infections have been registered, as experts from all over the world congregate in Cairo to discuss the SARS-like virus. According to the World Health Organization and Saudi authorities, 55 people have become infected with MERS-CoV, of whom 33 died. Worldwide there have been at least 70 (confirmed) infections and 39 deaths... (Source: Health News from Medical News Today)

Contemporary Topics in Pediatric Pulmonology for the Primary Care Clinician

Disorders of the respiratory system are commonly encountered in the primary care setting. The presentations are myriad and this review will discuss some of the more intriguing or vexing disorders that the clinician must evaluate and treat. Among these are dyspnea, chronic cough, chest pain, wheezing, and asthma. Dyspnea and chest pain have a spectrum ranging from benign to serious, and the ability to effectively form a differential diagnosis is critical for reassurance and treatment, along with decisions on when to refer for specialist evaluation. Chronic cough is one of the more common reasons for primary care office visits, and once again, a proper differential diagnosis is necessary to assist the clinician in formulating an appropriate treatment plan. Infant wheezing creates much anxiet...

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