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Current Readings: Pathology, Prognosis, and Lung Cancer

The 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma introduced the new categories of adenocarcinoma in situ, minimally invasive adenocarcinoma, and invasive mucinous adenocarcinoma, and replaced the category of mixed subtype adenocarcinoma with lepidic, acinar, papillary, micropapillary, and solid predominant adenocarcinoma. The aim of this manuscript is to evaluate whether the new classification can be applied successfully in determining prognosis of surgically resected patients. Six consecutive clinicopathologic studies using the new classification that were published between spring 2011 and fall 2012 were reviewed. Overall, they demonstrated excellent ...

Artificial Lung and Novel Devices for Respiratory Support

We present a brief description of the evolution of the use of ECMO in lung transplantation and summarize the available technology and current approaches to provide ECMO support. (Source: Seminars in Thoracic and Cardiovascular Surgery)

Anterior Chest Wall Resection and Reconstruction

Anterior chest wall resections may significantly alter the respiratory physiology depending on whether the entire sternum is involved, the size of the defect, and the type of reconstruction. Meticulous preoperative planning is necessary to effect radical resection and reconstruction according to the principles of biomimesis. To this end, computed tomography image reconstruction and digital subtraction are increasingly becoming a mandatory adjunct to visualize the extent of the chest wall involvement with special attention to tumor margins. To complete preoperative evaluation of tumors infiltrating the full thickness of the chest wall, a video-assisted thoracoscopic assessment of the inner chest wall can be useful, especially when chest wall recurrences from breast cancer or residual tumor ...

Middle East respiratory syndrome coronavirus (MERS-CoV) - update

Two patients earlier reported as laboratory-confirmed with Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Italy in the Disease Outbreak News on 2 June 2013 are being reclassified as probable cases. (Source: WHO Disease Outbreaks)

First Confirmed Case of Influenza 2013-2014: Alert for New Hampshire CliniciansFirst Confirmed Case of Influenza 2013-2014: Alert for New Hampshire Clinicians

The NH DPHS has confirmed the first respiratory sample positive for seasonal influenza virus in the New Hampshire Public Health Laboratories for this 2013-2014 season. State Health Alerts (Source: Medscape Today Headlines)

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