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Evaluation of the Chronic Obstructive Pulmonary Disease Assessment Test in Japanese Outpatients

ConclusionsThe CAT score, which is obtainable by a simple questionnaire originally designed for QOL assessment, had strong correlations with air flow obstruction, dyspnea, exercise tolerance, prognostic index, and oxygenation in Japanese outpatients. (Source: The Clinical Respiratory Journal)

Middle East respiratory syndrome coronavirus (MERS-CoV) - update

WHO has been informed of an additional laboratory-confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Qatar. (Source: WHO Disease Outbreaks)

Safety of bronchial thermoplasty in patients with severe refractory asthma.

CONCLUSION: Our findings suggest that BT is safe for 5 years after BT in patients with severe refractory asthma. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00401986. PMID: 24125149 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)

Characterization and treatment of patients with chronic rhinosinusitis and nasal polyps.

CONCLUSION: This study is one of the broadest reviews of patients with CRS+NP, with unique findings in the high prevalence of asthma in AS and AT patients, greater olfactory dysfunction in AS patients, and a minority of patients with CRS+NP and circulating eosinophils. Most AS patients do not have increased circulating eosinophils, as is often believed. These results shed further light on the association between asthma and upper respiratory tract disease in those with nasal polyposis. PMID: 24125137 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)

Association of tobacco smoke exposure and atopic sensitization.

CONCLUSION: These data suggest that ETS exposure was not associated with IgE sensitization to indoor allergens, even when home allergen levels were taken into consideration. Further understanding of how components of tobacco smoke influence the immune response is necessary to interpret the disparate findings across studies. PMID: 24125146 [PubMed - in process] (Source: Annals of Allergy, Asthma and Immunology)

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