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Inhaled Corticosteroids and the Risk of Pneumonia in People with Asthma: McKeever T, Harrison TW, Hubbard R, Shaw D. Chest 2013;144:1788−94.

Although there are studies demonstrating a relationship in chronic obstructive pulmonary disease of inhaled corticosteroid use and increased risk of pneumonia, these authors demonstrate a dose-dependent relationship between inhaled corticosteroids in asthma and increased risk of pneumonia and lower respiratory tract infections (LRTI) (p < 0.001 for trend). Through regression analysis of data from The Health Improvement Network the authors retrospectively analyzed data from a cohort and found 6857 patients with asthma and a LRTI. Patients that had asthma and smoked, had a higher Charlson Comorbidity Index score, used more frequent rescue inhalers, required more frequent oral steroid bursts, or were from a lower socioeconomic class, were more likely to develop pneumonia or LRTI. The authors ...

Efficacy of a multifactorial intervention on therapeutic adherence in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled trial

Conclusion: Application of the multifactorial intervention designed for this study (COPD information, dose reminders, audio-visual material, motivational aspects and training in inhalation techniques) resulted in an improvement in therapeutic adherence in COPD patients with scheduled inhalation therapy.Trial registration: Current Controlled Trials ISRCTN18841601. (Source: BioMed Central)

Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study

Conclusions: Histories of asthma, allergic rhinitis, acute bronchitis, current smoking, a lower FEV1%, Caucasian race, male gender, and increased airway wall thickness are associated with CB. These data provide clinical and radiologic correlations to the clinical phenotype of CB. (Source: Respiratory Research)

Electronic Cigarettes: Q&A

Title: Electronic Cigarettes: Q&ACategory: Health NewsCreated: 4/26/2014 11:03:00 AMLast Editorial Review: 4/28/2014 12:00:00 AM (Source: MedicineNet Lungs General)

Preterm nutrition and the lung.

Authors: Moya F Abstract Experimental and clinical evidence show that fetal and neonatal nutrition and metabolism can markedly modulate pulmonary growth, development, and function, as well as long-term lung health and disease risks. Intrauterine growth restriction has been linked to an increased risk for respiratory distress syndrome and chronic lung disease, while excessive fetal growth reduced forced expiratory volume. Postnatal undernutrition adversely affected pulmonary function in animal models and was associated to a higher risk of chronic lung disease in very low birth weight infants. The supply of specific nutrients to very low birth weight infants, including fluids, protein, carbohydrates, inositol, docosahexaenoic acid, calcium, phosphorus and the vitamins A and E has bee...

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