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Single-dose dexamethasone for mild-to-moderate asthma exacerbations: Effective, easy, and acceptable.

Question I prescribe oral steroids for children in my community when they suffer asthma exacerbation. How many doses of steroids are recommended? Do all children need to take steroids for 5 days? Answer Traditionally, mild-to-moderate pediatric asthma exacerbations have been treated with a short course of oral steroids-often 5 days of prednisone or prednisolone.

However, recent evidence suggests a similar outcome can be acheived with a single dose of dexamethasone, which has a longer half-life and powerful anti-inflammatory effects, along with easier administration and compliance.

Single-dose dexamethasone offers a simple and reliable treatment for these patients in office, urgent care, and emergency department settings.

Can Fam Physician. 2011 Oct;57(10):1134-6
Authors: Cross KP, Paul RI, Goldman RD
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