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Clinical performance of three rapid diagnostic tests for influenza virus in nasopharyngeal specimens to detect novel swine-origin influenza viruses

Influenza is an important public health problem. The aim of this study was to evaluate and compare the sensitivity and specificity of three rapid diagnostic tests (SEKISUI, QuickVue Influenza A + B, and SD BIOLINE) for novel swine-origin influenza viruses (S-OIV) and seasonal influenza.

Materials and methods  A total of 210 nasopharyngeal swabs from unique clinical specimens were previously tested by real-time reverse transcription polymerase chain reaction (RT-PCR) assay and tested again in this study.

Results and discussion  Of these, 164 (78%) were influenza A-positive and 46 (22%) were influenza A-negative by RT-PCR. From 115 positive swabs, 80 (69.6%), 66 (57.4%), and 46 (40.0%) showed S-OIV by SEKISUI...

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