The broad applicability of allergen‐specific immunotherapy for the treatment and eventually prevention of IgE‐mediated allergy is limited by the poor quality and allergenic activity of natural allergen extracts that are used for the production of current allergy vaccines.

Today, the genetic code of the most important allergens has been deciphered; recombinant allergens equalling their natural counterparts have been produced for diagnosis and immunotherapy, and a large panel of genetically modified allergens with reduced allergenic...

Author:Valenta R, Linhart B, Swoboda I, Niederberger V.
Allergy 2011; DOI:10.1111/j.1398‐9995.2011.02565
Read Full Article