This paper defines the molecular mechanisms of two subtypes of asthma—Th2/Th17-predominant asthma and Th2/Th17-low, neutrophilic asthma. The paper also delineates phenotype-specific therapeutic agents that are likely benefit these two subtypes of asthma.
Author:Weimin Liu, Sucai Liu, Mukesh Verma, Iram Zafar, James T. Good, Donald Rollins, Stephen Groshong, Magdalena M. Gorska, Richard J. Martin, Rafeul Alam