WHO Strategies for the programmatic management of drug-resistant tuberculosis.

Expert Rev Respir Med. 2016 Jun 8;

Authors: Matteelli A, Centis R, D'Ambrosio L, Sotgiu G, Tadolini M, Pontali E, Spanevello A, Migliori GB

Abstract
Adequate management of drug-resistant tuberculosis (TB), including multidrug- (MDR-) and extensively drug-resistant (XDR-)TB are within the priorities of the newly launched World Health Organization's End TB and Elimination Strategies. This manuscript aims to present the evidence on the MDR- /XDR-TB epidemiology and to discuss how the five recommended priority actions can be applied at the programmatic level to tackle the epidemic: 1) Prevent development of MDR-TB thorough high quality treatment of drug- susceptible TB; 2) Expand rapid testing and detection of drug-resistant TB; 3) Provide immediate access to effective treatment and proper care; 4) Prevent transmission through infection control; 5) Increase political commitment and financing. A non-systematic review of the available literature was performed to provide the reader with a comprehensive view on the topic.

PMID: 27276361 [PubMed - as supplied by publisher]