The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Prevention of Allergic Disease. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the prevention of allergic disease.
METHODS: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.
DISCUSSION: The findings from this review will be used to inform the development of recomendations for EAACI's Guidelines on AIT. This article is protected by copyright. All rights reserved.
Pediatr Allergy Immunol. 2015 Dec 12;
Authors: Dhami S, Nurmatov U, Halken S, Calderón MA, Muraro A, Roberts G, Du Toit G, Kleine-Tebbe J, Larenas-Linnemann D, Lau S, Matricardi PM, Pajno G, Papadopoulos NG, Pfaar O, Ryan D, Santos AF, Timmermanns F, Wahn U, Sheikh A